Unmasking the tonic-aversive state in neuropathic pain
نویسندگان
چکیده
منابع مشابه
Altered Resting State in Diabetic Neuropathic Pain
BACKGROUND The spontaneous component of neuropathic pain (NP) has not been explored sufficiently with neuroimaging techniques, given the difficulty to coax out the brain components that sustain background ongoing pain. Here, we address for the first time the correlates of this component in an fMRI study of a group of eight patients suffering from diabetic neuropathic pain and eight healthy cont...
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Chronic neuropathic pain is a common significant and debilitating problem that presents a major challenge to health-care. Despite the large number of available drugs, there are no curative conventional treatments for neuropathic pain. Nowadays, more attention has been focused on the herbal formulation in the field of drug discovery. Therefore, we performed an extensive review about herbal drugs...
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Neuropathic pain results from damage to, or dysfunction of, the system that normally signals pain. The International Association for the Study of Pain (IASP 2007) defines neuropathic pain as follows: ‘Pain initiated or caused by a primary lesion or dysfunction in the nervous system. Peripheral neuropathic pain occurs when the lesion or dysfunction affects the peripheral nervous system. Central ...
متن کاملAltered resting state attentional networks in diabetic neuropathic pain.
BACKGROUND Chronic pain can be considered as a highly salient stimulus that continuously taxes the attentional and salience processing networks, thus interfering with cognitive abilities and, more specifically, consuming attentional resources. The aim of the paper was to explore whether and how diabetic neuropathic pain (NP) affects attentional networks. METHODS The authors sought to achieve ...
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Pain perception is closely related to the attentional level and the vigilance of the subject [4]. The intensity of a pain stimulus and its sensation do often not coincide. A common experimental example is the so-called pain-inhibiting-pain effect: A stressful stimulus, e.g. persistent or chronic pain, often elevates the threshold for brief pain stimuli applied during the same time. Stressful st...
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2009
ISSN: 1097-6256,1546-1726
DOI: 10.1038/nn.2407